The world can't get enough of Giuliana Rancic. The lighthearted E! News host balances a gig on Fashion Police, designing for her G by Giuliana Rancic clothing collection for HSN, and overseeing her women’s lifestyle site, fabfitfun.com. Even more magnetic than her cheerful personality and go-getter attitude, is her ability to overcome life’s curveballs: her and husband Bill Rancic have shared their struggles with infertility, as well as Giuliana’s 2011 breast cancer diagnosis, through their reality show, Giuliana & Bill. But after undergoing a double mastectomy and welcoming son Edward Duke with the help of a gestational carrier, the couple couldn't be happier.

While in town for the Cotton 24-Hour Runway Show, we stole a few moments with the busy new mom to talk season six of Giuliana & Bill, life advice, and Miami date-nights. 

Are you and Bill going to have a Miami date-night while you’re here for the Cotton fashion show?
GIULIANA RANCIC: Yes! We always manage to get a date-night in no matter where we go. We had a delicious dinner at Nobu and a yummy dessert at Serendipity.

Has anything on the Cotton runway caught your eye?
GR: I loved all the cotton wedding gowns. What a smart idea for a wedding dress. To be comfortable and look gorgeous and fresh on your wedding day is a no-brainer.

What can we expect on season six of Giuliana & Bill?  
GR: We are currently in production of Giuliana & Bill, which premieres in June. There will be a lot of baby Duke, as well as our new home in Los Angeles. We also had the cameras with us in Miami at Cotton’s 24-Hour Runway show, so we will definitely be showing off gorgeous Miami.

Tell us about your spring collection for HSN, which comes out this month.
GR: It's all about bright colors and fun prints—the brighter and bolder the colors, the better.

You have a lot of titles—host, author, mom, designer, business owner, spokeswoman. Any thoughts on what's next? Maybe a line for babies?
GR: I would love to get into the baby furniture and clothing business. I feel like there is such a void for super stylish yet very cozy and affordable baby clothes and have so many ideas that I am having a hard time containing. As for baby furniture, I have several fun prints and concepts I would love to create to help people have a super stylish yet peaceful nursery.

What’s the best advice you’ve ever received?
GR: I love the quote, ‘Everything will be okay in the end. If it’s not okay, it’s not the end.’

And what’s you’re best piece of advice to give?
GR: When life pushes me, I push back—harder.